Cutler immediately threw another interception, and Glover Quin returned it 42 yards to the Chicago 2-yard line. Stafford threw a 2-yard TD to Calvin Johnson.
Bush burst through a huge hole and hurdled safety Major Wright to give the Lions a 30-10 lead.
Stafford completed 23 of 35 passes for 242 yards. He did throw an interception, and his fumble late in the first half helped Chicago add a field goal to make it 30-13 after two quarters.
The Bears kicked another field goal midway through the third quarter to pull within two TDs, but Cutler hurt the Bears when his up-for-grabs pass was picked off by safety Louis Delmas, who had two interceptions.
“Although he’s a great quarterback with a strong arm, sometimes we can read him, and we got the better of him,” Delmas said.
Cutler said his mistakes were physical, not mental.
“I felt good about my decision making,” he said. “I just missed some throws.”
Stafford turned the ball over again when his low pass intended for Johnson deep in Chicago territory was kicked up in the air and intercepted by Wright.
But Suh sacked Cutler and forced a fumble fellow defensive tackle Nick Fairley recovered and returned 4 yards for a score that put Detroit up 37-16 late in the third period.
Cutler went 27 of 47. He threw a 14-yard TD pass to Alshon Jeffery with 4 minutes left, and a 2-point conversion pass to Jeffrey pulled Chicago within 16 points.
Cutler threw a 10-yard TD pass to Earl Bennett with 43 seconds to go and connected with Brandon Marshall for a 2-point conversion that made it 40-32.
“I watched the demeanor of our football team on the sideline during the last 30 minutes of the game,” Trestman said. “I thought it was excellent. Guys were fighting, guys were in it. They were focused. There was a sense of urgency there.”