The Clinton Herald, Clinton, Iowa

Top News

June 19, 2013

To ease shortage, grow organs in a lab?

NEW YORK — By the time 10-year-old Sarah Murnaghan finally got a lung transplant last week, she’d been waiting for months, and her parents had sued to give her a better shot at surgery.

Her cystic fibrosis was threatening her life, and her case spurred a debate on how to allocate donor organs. Lungs and other organs for transplant are scarce.

But what if there were another way? What if you could grow a custom-made organ in a lab?

It sounds incredible. But just a three-hour drive from the Philadelphia hospital where Sarah got her transplant, another little girl is benefiting from just that sort of technology. Two years ago, Angela Irizarry of Lewisburg, Pa., needed a crucial blood vessel. Researchers built her one in a laboratory, using cells from her own bone marrow. Today the 5-year-old sings, dances and dreams of becoming a firefighter — and a doctor.

Growing lungs and other organs for transplant is still in the future, but scientists are working toward that goal. In North Carolina, a 3-D printer builds prototype kidneys. In several labs, scientists study how to build on the internal scaffolding of hearts, lungs, livers and kidneys of people and pigs to make custom-made implants.

Here’s the dream scenario: A patient donates cells, either from a biopsy or maybe just a blood draw. A lab uses them, or cells made from them, to seed onto a scaffold that’s shaped like the organ he needs. Then, says Dr. Harald Ott of Massachusetts General Hospital, “we can regenerate an organ that will not be rejected (and can be) grown on demand and transplanted surgically, similar to a donor organ.”

That won’t happen anytime soon for solid organs like lungs or livers. But as Angela Irizarry’s case shows, simpler body parts are already being put into patients as researchers explore the possibilities of the field.

Text Only
Top News
  • Celebrity quack moms are a terrible influence on everyday parents

    On April 15, the actress Alicia Silverstone released a book called "The Kind Mama: A Simple Guide to Supercharged Fertility, a Radiant Pregnancy, a Sweeter Birth, and a Healthier, More Beautiful Beginning." It's chock-full of attachment parenting lessons and dangerous misinformation.

    April 24, 2014

  • Lindley, Tom.jpg What will happen in NFL draft? No one really knows

    Despite the hours spent interviewing coaches, watching film and developing well-reasoned mock draft lists, the truth about the 2014 NFL draft remains a mystery, well-guarded by teams that have nothing to gain by publicly sharing their innermost thoughts.

    April 24, 2014 1 Photo

  • American sunscreens need an upgrade

    The last time a new sunscreen ingredient came on the U.S. market, the Y2K bug was threatening to destroy our way of life. Intel had just introduced the Pentium III processor, featuring an amazing 500 MHz of computing power.

    April 24, 2014

  • 20140424-AMX-COFFEE24.jpg Coffee growers' prayers for rain met with threat of deluge

    Brazil's drought made arabica coffee this year's best-performing commodity. Now, farmers are facing a downpour that is once more threatening crops.

    April 24, 2014 1 Photo

  • Iowa man accused of torturing, killing bald eagle

    An Iowa man has been charged with torturing and killing a bald eagle.

    A federal grand jury in Des Moines returned an indictment Wednesday against Jason John Thomas.

    April 24, 2014

  • Affirmative action ruling challenges colleges seeking diversity

    The U.S. Supreme Court's support of Michigan's ban on race-based affirmative action in university admissions may spur colleges to find new ways to achieve diversity without using racial preferences.

    April 24, 2014

  • 10 Things to Know for Today

    Your daily look at late-breaking news, upcoming events and the stories that will be talked about today:

    April 24, 2014

  • 4-23-14 Northey Burkens committed to ag education CLINTON -- As the Iowa Secretary of Agriculture, Bill Northey said his department doesn't hand out the Good Farm Neighbor Award arbitrarily. Only 10 acknowledgements are bestowed each year. On Wednesday, the honor went to a worthy family in Clinton C

    April 24, 2014 2 Photos

  • World Book Night 1 Clinton Public Library hosts largest World Book Night event in the country

    CLINTON -- With more than 21 titles and 800 copies to give away, what reader wouldn't adore an event like World Book Night? Organizers at the Clinton Public Library wondered the same Wednesday, and were pleased with turnout for the third annual event

    April 24, 2014 1 Photo

  • Amid Russian warning, Ukraine's in a security bind

    Ukraine's highly publicized goal to recapture police stations and government buildings seized by pro-Russia forces in the east produced little action on the ground Wednesday but ignited foreboding words from Moscow.

    Russian Foreign Minister Sergey Lavrov warned that Russia would mount a firm response if its citizens or interests come under attack in Ukraine. Although he did not specifically say Russia would launch a military attack, his comments bolstered wide concern that Russia could use any violence in eastern Ukraine as a pretext for sending in troops.

    April 23, 2014

AP Video